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CELL ADHESION AND CANCER LAB

Integrins, matrix, motility and mechanotransduction in cancer

WELCOME TO OUR LAB

We are interested in understanding how integrins contribute to almost every step of cancer progression. Current projects focus on finding novel regulators of integrin activity, and endo/exosomal traffic, and on appreciating the mechanisms controlling tumour-stroma cross-talk, including how cancer cells sense key biophysical cues. We are also investigating signal integration and synergy between integrin regulatory pathways and oncogenic signalling axes in cancer.

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OUR RESEARCH

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Microenvironmental containment of tumors

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Cell adhesion and cancer

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Integrin trafficking

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Receptor tyrosine kinase trafficking

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Biophysical regulation of cancer cells

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Imaging metastasis

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Tools for mechanobiology

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Recent publications

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