CELL ADHESION AND CANCER LAB

Integrins, matrix, motility and mechanotransduction in cancer

WELCOME TO OUR LAB

We are interested in understanding how integrins contribute to almost every step of cancer progression. Current projects focus on finding novel regulators of integrin activity, and endo/exosomal traffic, and on appreciating the mechanisms controlling tumour-stroma cross-talk, including how cancer cells sense key biophysical cues. We are also investigating signal integration and synergy between integrin regulatory pathways and oncogenic signalling axes in cancer.

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OUR RESEARCH

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Microenvironmental containment of tumors

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Cell adhesion and cancer

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Integrin trafficking

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Receptor tyrosine kinase trafficking

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Biophysical regulation of cancer cells

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Imaging metastasis

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Tools for mechanobiology

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Recent news

Johanna becomes a member of Academia Europaea!

Friday, June 02, 2023

Worldwide Cancer Research funding!

Monday, May 29, 2023

We have a new Postdoc and PhD student! Welcome both!

Friday, June 10, 2022

Recent publications

Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton by Amy E M Beedle et al.

Tuesday, November 21, 2023

Dynamic Micropatterning Reveals Substrate-Dependent Differences in the Geometric Control of Cell Polarization and Migration by Aleksi Isomursu et al.

Sunday, November 05, 2023

Defined extracellular matrix compositions support stiffness-insensitive cell spreading and adhesion signaling by James R W Conway et al.

Monday, October 16, 2023