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Cell Adhesion and Cancer Laboratory

Integrins, matrix, motility and mechanotransduction in cancer

Welcome to our lab

We are interested in understanding how integrins contribute to almost every step of cancer progression. Current projects focus on finding novel regulators of integrin activity, and endo/exosomal traffic, and on appreciating the mechanisms controlling tumour-stroma cross-talk, including how cancer cells sense key biophysical cues. We are also investigating signal integration and synergy between integrin regulatory pathways and oncogenic signalling axes in cancer.

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Our research

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Microenvironmental containment of tumors

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Cell adhesion and cancer

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Integrin trafficking

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Receptor tyrosine kinase trafficking

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Biophysical regulation of cancer cells

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Imaging metastasis

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Tools for mechanobiology

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The link between cell states and disease

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Recent publications

Tuesday, October 29, 2024
Cell. 2024 Oct 22:S0092-8674(24)01146-2. doi: 10.1016/j.cell.2024.09.046. On...
Monday, October 07, 2024
bioRxiv [Preprint]. 2024 Aug 23:2024.08.22.609159. doi: 10.1101/2024.08.22.6...
Monday, September 30, 2024
Nat Rev Mol Cell Biol. 2024 Sep 30. doi: 10.1038/s41580-024-00777-1. Online ...
Thursday, September 12, 2024
Nat Commun. 2024 Sep 12;15(1):8002. doi: 10.1038/s41467-024-52326-1. ABSTRAC...
Tuesday, July 16, 2024
J Cell Biol. 2024 Sep 2;223(9):e202310030. doi: 10.1083/jcb.202310030. Epub ...
Monday, April 22, 2024
J Cell Sci. 2024 Apr 15;137(8):jcs261919. doi: 10.1242/jcs.261919. Epub 2024...
Wednesday, April 17, 2024
Curr Opin Cell Biol. 2024 Apr 16;88:102355. doi: 10.1016/j.ceb.2024.102355. ...
Friday, March 22, 2024
Nat Commun. 2024 Mar 21;15(1):2547. doi: 10.1038/s41467-024-46868-7. ABSTRAC...

Recent news

Monday, September 23, 2024
Congratulations, Nicolas, on successfully defending...
Tuesday, April 16, 2024
We proudly announce that the lab has received an ER...
Friday, April 12, 2024
Congratulations, Aleksi, on successfully defending ...
Friday, June 02, 2023
Johanna has been appointed a member of the Academia...
Monday, May 29, 2023
We are very excited to receive funding from WWCR to...
Wednesday, March 01, 2023
Michal received his Marie Skłodowska-Curie Actions ...